小鼠抗cox6c单ke隆抗体

backg

round:

cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. it is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes&multiple structural subunits encoded by nuclear genes. the mitochondrially-encoded subunits function in electron transfer,&the nuclear-encoded subunits may be involved in the regulation&assembly of the complex. this nuclear gene encodes subunit vic, which has 77% amino acid sequence identity with mouse subunit vic. this gene is up-regulated in prostate cancer cells. a pseudogene has been found on chromosomes 16p12. [provided by refseq, jul

applic

ations:

wb, ihc, if

name of a

ntibody:

cox6c

immunogen:

fusion protein of human cox6c

full name:

cytochrome c oxidase subunit vic (cox6c)

synonyms:

cytochrome c oxidase subunit vic preprotein; cytochrome c oxidase subunit vic

swissprot:

p09669

ihc posit

ive control:

adenocarcinoma of human ovary tissue&human pancreas tissue; adenocarcinoma of human endometrium tissue&adenocarcinoma of human breast tissue

ihc recom

mend dilution:

30-150

wb predi

ted band size:

9 kda

wb positive control:

nih/3t3 cell, mouse brain tissue, mouse liver tissue, mouse spleen tissue lysates

wb recom

mended dilution:

200-1000